P122 Association between variability of respiratory sleep indices and ambulatory blood pressure

Abstract Study Objectives Respiratory sleep indices are traditionally reported on the basis of average total time. The relationship between hour-to-hour variability these parameters and blood pressure (BP) has not been reported. Methods We evaluated associations apnea–hypopnea index (AHI), oxygen desaturation (ODI), lowest saturation with 24-hour ambulatory BP in patients hypertension newly diagnosed obstructive apnea. A 147 underwent polysomnography, based which apnea was 106 monitoring within next 30 days. Each polysomnogram divided into hourly reports to calculate respiratory indices. Variability independent mean considered primary measure variability. Results median number 7 (range, 4–8).The both AHI ODI, but saturation, correlated pulse pressure, systolic BP, awake (p < 0.05 for all). fully adjusted linear regression analysis indicated that ODI remained associated (AHI: β coefficient, 0.264 [95% CI, 0.033–0.495],p =0.026; ODI: 0.450 0.174 - -0.726],p = 0.002). Conclusions is independently pressure. Further investigations warranted evaluate clinical relevance this new-found association.